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A drug screening toolkit based on the –1 ribosomal frameshifting of SARS-CoV-2

The –1 ribosomal frameshifting is vital for the translation of the open reading frame (ORF)1b in SARS-CoV-2. The products of ORF1b participate in viral replication. Therefore, changing the frameshift frequency reduces the survival of the virus. This study aimed to successfully develop a toolkit for...

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Detalles Bibliográficos
Autores principales:	Chen, Yanqiong, Tao, Huan, Shen, Silan, Miao, Zhiyong, Li, Lili, Jia, Yongqian, Zhang, Hu, Bai, Xiufeng, Fu, Xinyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448739/ https://www.ncbi.nlm.nih.gov/pubmed/32869005 http://dx.doi.org/10.1016/j.heliyon.2020.e04793

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