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COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil

COVID-19 pandemic has been a problem worldwide. It is important to identify people at risk of progressing to severe complications and to investigate if some existing antivirals could have any action against SARS-CoV-2. In this context, HIV-infected individuals and antiretroviral drugs might be inclu...

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Detalles Bibliográficos
Autores principales: Cipolat, Murillo Machado, Sprinz, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448763/
https://www.ncbi.nlm.nih.gov/pubmed/32866436
http://dx.doi.org/10.1016/j.bjid.2020.07.009
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author Cipolat, Murillo Machado
Sprinz, Eduardo
author_facet Cipolat, Murillo Machado
Sprinz, Eduardo
author_sort Cipolat, Murillo Machado
collection PubMed
description COVID-19 pandemic has been a problem worldwide. It is important to identify people at risk of progressing to severe complications and to investigate if some existing antivirals could have any action against SARS-CoV-2. In this context, HIV-infected individuals and antiretroviral drugs might be included, respectively. Herein we present the case of a 63-year-old HIV-infected woman with undetectable viral load, on dolutegravir, tenofovir and lamivudine, who was hospitalized due to COVID-19 pneumonia. In spite of having some clinical markers of severity on admission, the patient improved and was discharged after a week. To our knowledge, this is the first report of severe SARS-CoV-2 infection in an HIV-infected individual in Brazil.
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spelling pubmed-74487632020-08-27 COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil Cipolat, Murillo Machado Sprinz, Eduardo Braz J Infect Dis Case Report COVID-19 pandemic has been a problem worldwide. It is important to identify people at risk of progressing to severe complications and to investigate if some existing antivirals could have any action against SARS-CoV-2. In this context, HIV-infected individuals and antiretroviral drugs might be included, respectively. Herein we present the case of a 63-year-old HIV-infected woman with undetectable viral load, on dolutegravir, tenofovir and lamivudine, who was hospitalized due to COVID-19 pneumonia. In spite of having some clinical markers of severity on admission, the patient improved and was discharged after a week. To our knowledge, this is the first report of severe SARS-CoV-2 infection in an HIV-infected individual in Brazil. Elsevier 2020-08-26 /pmc/articles/PMC7448763/ /pubmed/32866436 http://dx.doi.org/10.1016/j.bjid.2020.07.009 Text en © 2020 Sociedade Brasileira de Infectologia. Published by Elsevier España, S.L.U. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Cipolat, Murillo Machado
Sprinz, Eduardo
COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
title COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
title_full COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
title_fullStr COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
title_full_unstemmed COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
title_short COVID-19 pneumonia in an HIV-positive woman on antiretroviral therapy and undetectable viral load in Porto Alegre, Brazil
title_sort covid-19 pneumonia in an hiv-positive woman on antiretroviral therapy and undetectable viral load in porto alegre, brazil
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448763/
https://www.ncbi.nlm.nih.gov/pubmed/32866436
http://dx.doi.org/10.1016/j.bjid.2020.07.009
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