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Biosafety considerations and risk reduction strategy for a new veterinary faculty building and teaching hospital in Sweden

INTRODUCTION: This paper describes a hazard- and risk-based strategy and recommendations on relevant biosafety levels in facility design of a new veterinary faculty building including a veterinary medical teaching hospital. Both animal and human health were considered. MATERIALS AND METHODS: Agents...

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Autores principales: Wierup, Martin, Allard Bengtsson, Ulrika, Vågsholm, Ivar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448862/
https://www.ncbi.nlm.nih.gov/pubmed/32864050
http://dx.doi.org/10.1080/20008686.2020.1761588
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author Wierup, Martin
Allard Bengtsson, Ulrika
Vågsholm, Ivar
author_facet Wierup, Martin
Allard Bengtsson, Ulrika
Vågsholm, Ivar
author_sort Wierup, Martin
collection PubMed
description INTRODUCTION: This paper describes a hazard- and risk-based strategy and recommendations on relevant biosafety levels in facility design of a new veterinary faculty building including a veterinary medical teaching hospital. Both animal and human health were considered. MATERIALS AND METHODS: Agents listed in the regulatory frameworks on animal and human health were identified as the main potential hazards. Suggestions on biosafety level and facility design were based on the official risk grouping of those agents, the associated risk management procedures, and biosafety experiences from previous faculty buildings. RESULTS AND DISCUSSION: It was suggested that VHC should not be designed for work with agents requiring facilities at biosafety levels 3 and 4, and that actions in cases of accidental exposure to notifiable infections should follow the regulatory requirements. Facilities requiring biosafety level 2 were identified from risk scenarios and transmission routes. Experiences from the first five years of operation revealed good prevention of spread of infection from patients in isolation facilities and successful elimination of Salmonella and MRSA from the large animal clinic. CONCLUSION: In order to avoid costly construction mistakes, an overall biosafety strategy should be formulated and used as guidance for architects and other relevant stakeholders designing facilities for the animal health sector. Regulatory requirements on infectious diseases must be complied with.
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spelling pubmed-74488622020-08-28 Biosafety considerations and risk reduction strategy for a new veterinary faculty building and teaching hospital in Sweden Wierup, Martin Allard Bengtsson, Ulrika Vågsholm, Ivar Infect Ecol Epidemiol Research Article INTRODUCTION: This paper describes a hazard- and risk-based strategy and recommendations on relevant biosafety levels in facility design of a new veterinary faculty building including a veterinary medical teaching hospital. Both animal and human health were considered. MATERIALS AND METHODS: Agents listed in the regulatory frameworks on animal and human health were identified as the main potential hazards. Suggestions on biosafety level and facility design were based on the official risk grouping of those agents, the associated risk management procedures, and biosafety experiences from previous faculty buildings. RESULTS AND DISCUSSION: It was suggested that VHC should not be designed for work with agents requiring facilities at biosafety levels 3 and 4, and that actions in cases of accidental exposure to notifiable infections should follow the regulatory requirements. Facilities requiring biosafety level 2 were identified from risk scenarios and transmission routes. Experiences from the first five years of operation revealed good prevention of spread of infection from patients in isolation facilities and successful elimination of Salmonella and MRSA from the large animal clinic. CONCLUSION: In order to avoid costly construction mistakes, an overall biosafety strategy should be formulated and used as guidance for architects and other relevant stakeholders designing facilities for the animal health sector. Regulatory requirements on infectious diseases must be complied with. Taylor & Francis 2020-06-04 /pmc/articles/PMC7448862/ /pubmed/32864050 http://dx.doi.org/10.1080/20008686.2020.1761588 Text en © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wierup, Martin
Allard Bengtsson, Ulrika
Vågsholm, Ivar
Biosafety considerations and risk reduction strategy for a new veterinary faculty building and teaching hospital in Sweden
title Biosafety considerations and risk reduction strategy for a new veterinary faculty building and teaching hospital in Sweden
title_full Biosafety considerations and risk reduction strategy for a new veterinary faculty building and teaching hospital in Sweden
title_fullStr Biosafety considerations and risk reduction strategy for a new veterinary faculty building and teaching hospital in Sweden
title_full_unstemmed Biosafety considerations and risk reduction strategy for a new veterinary faculty building and teaching hospital in Sweden
title_short Biosafety considerations and risk reduction strategy for a new veterinary faculty building and teaching hospital in Sweden
title_sort biosafety considerations and risk reduction strategy for a new veterinary faculty building and teaching hospital in sweden
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448862/
https://www.ncbi.nlm.nih.gov/pubmed/32864050
http://dx.doi.org/10.1080/20008686.2020.1761588
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