Cargando…

Unraveling the Mechanism of the Antitumor Activity of Bacillus Calmette-Guérin

Our understanding of the mechanism of bacillus Calmette-Guérin (BCG) in controlling urothelial carcinoma is still evolving. Studies have revealed a complex and multifaceted immune response. BCG-elicited adaptive antitumor immunity directed towards tumor antigens could have major implications for tri...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Roger, Gilbert, Scott M., Kamat, Ashish M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. on behalf of European Association of Urology. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448869/
https://www.ncbi.nlm.nih.gov/pubmed/32861573
http://dx.doi.org/10.1016/j.eururo.2020.08.027
_version_ 1783574557956767744
author Li, Roger
Gilbert, Scott M.
Kamat, Ashish M.
author_facet Li, Roger
Gilbert, Scott M.
Kamat, Ashish M.
author_sort Li, Roger
collection PubMed
description Our understanding of the mechanism of bacillus Calmette-Guérin (BCG) in controlling urothelial carcinoma is still evolving. Studies have revealed a complex and multifaceted immune response. BCG-elicited adaptive antitumor immunity directed towards tumor antigens could have major implications for trial design.
format Online
Article
Text
id pubmed-7448869
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Published by Elsevier B.V. on behalf of European Association of Urology.
record_format MEDLINE/PubMed
spelling pubmed-74488692020-08-27 Unraveling the Mechanism of the Antitumor Activity of Bacillus Calmette-Guérin Li, Roger Gilbert, Scott M. Kamat, Ashish M. Eur Urol Article Our understanding of the mechanism of bacillus Calmette-Guérin (BCG) in controlling urothelial carcinoma is still evolving. Studies have revealed a complex and multifaceted immune response. BCG-elicited adaptive antitumor immunity directed towards tumor antigens could have major implications for trial design. Published by Elsevier B.V. on behalf of European Association of Urology. 2020-08-26 /pmc/articles/PMC7448869/ /pubmed/32861573 http://dx.doi.org/10.1016/j.eururo.2020.08.027 Text en © 2020 Published by Elsevier B.V. on behalf of European Association of Urology. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Li, Roger
Gilbert, Scott M.
Kamat, Ashish M.
Unraveling the Mechanism of the Antitumor Activity of Bacillus Calmette-Guérin
title Unraveling the Mechanism of the Antitumor Activity of Bacillus Calmette-Guérin
title_full Unraveling the Mechanism of the Antitumor Activity of Bacillus Calmette-Guérin
title_fullStr Unraveling the Mechanism of the Antitumor Activity of Bacillus Calmette-Guérin
title_full_unstemmed Unraveling the Mechanism of the Antitumor Activity of Bacillus Calmette-Guérin
title_short Unraveling the Mechanism of the Antitumor Activity of Bacillus Calmette-Guérin
title_sort unraveling the mechanism of the antitumor activity of bacillus calmette-guérin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448869/
https://www.ncbi.nlm.nih.gov/pubmed/32861573
http://dx.doi.org/10.1016/j.eururo.2020.08.027
work_keys_str_mv AT liroger unravelingthemechanismoftheantitumoractivityofbacilluscalmetteguerin
AT gilbertscottm unravelingthemechanismoftheantitumoractivityofbacilluscalmetteguerin
AT kamatashishm unravelingthemechanismoftheantitumoractivityofbacilluscalmetteguerin