Particulate multivalent presentation of the receptor binding domain induces protective immune responses against MERS-CoV

Middle East respiratory syndrome coronavirus (MERS-CoV) is a WHO priority pathogen for which vaccines are urgently needed. Using an immune-focusing approach, we created self-assembling particles multivalently displaying critical regions of the MERS-CoV spike protein ─fusion peptide, heptad repeat 2,...

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Detalles Bibliográficos
Autores principales: Okba, Nisreen M. A., Widjaja, Ivy, van Dieren, Brenda, Aebischer, Andrea, van Amerongen, Geert, de Waal, Leon, Stittelaar, Koert J., Schipper, Debby, Martina, Byron, van den Brand, Judith M. A., Beer, Martin, Bosch, Berend-Jan, Haagmans, Bart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448924/
https://www.ncbi.nlm.nih.gov/pubmed/32471334
http://dx.doi.org/10.1080/22221751.2020.1760735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448924/
https://www.ncbi.nlm.nih.gov/pubmed/32471334
http://dx.doi.org/10.1080/22221751.2020.1760735

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