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Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors
Enterovirus A71 (EV-A71), a positive-stranded RNA virus of the Picornaviridae family, may cause neurological complications or fatality in children. We examined specific factors responsible for this virulence using a chemical genetics approach. Known compounds from an anti-EV-A71 herbal medicine, Sal...
Autores principales: | Hsieh, Chung-Fan, Jheng, Jia-Rong, Lin, Guan-Hua, Chen, Yu-Li, Ho, Jin-Yuan, Liu, Chien-Jou, Hsu, Kuei-Yang, Chen, Yuan-Siao, Chan, Yoke Fun, Yu, Hui-Ming, Hsieh, Pei-Wen, Chern, Jyh-Haur, Horng, Jim-Tong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448925/ https://www.ncbi.nlm.nih.gov/pubmed/32397909 http://dx.doi.org/10.1080/22221751.2020.1767512 |
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