Novel genetic alteration in congenital melanocytic nevus: MAP2K1 germline mutation with BRAF somatic mutation

Congenital melanocytic nevus (CMN) represent a benign proliferative skin disease in the epidermis and dermis. CMN are historically known to be associated with activating NRAS or BRAF mutations. Melanoma frequently harbors the BRAF p.Val600Glu mutation, which is also commonly found in benign nevi. A...

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Detalles Bibliográficos
Autores principales: Zou, Yun, Sun, Yi, Zeng, Xiaojing, Liu, Yun, Cen, Qingqing, Gu, Hao, Lin, Xiaoxi, Cai, Ren, Chen, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449081/
https://www.ncbi.nlm.nih.gov/pubmed/32847629
http://dx.doi.org/10.1186/s41065-020-00147-9

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