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Comparación de la escala qSOFA para evaluar la falla orgánica secuencial y los criterios SIRS para sepsis a la cabecera de pacientes con bacteriemia por Staphylococcus aureus

INTRODUCTION: One of the primary causes of community-acquired bacteremia also associated with nosocomial infections is Staphylococcus aureus, which is responsible for a high percentage of complications leading to high morbidity and mortality rates. The systemic inflammatory response syndrome (SIRS)...

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Autores principales: García, Óscar, Álvarez, Tatiana, Granados, Santiago, Garzón, Vanessa, González, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Nacional de Salud 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449100/
https://www.ncbi.nlm.nih.gov/pubmed/32463614
http://dx.doi.org/10.7705/biomedica.4943
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author García, Óscar
Álvarez, Tatiana
Granados, Santiago
Garzón, Vanessa
González, Santiago
author_facet García, Óscar
Álvarez, Tatiana
Granados, Santiago
Garzón, Vanessa
González, Santiago
author_sort García, Óscar
collection PubMed
description INTRODUCTION: One of the primary causes of community-acquired bacteremia also associated with nosocomial infections is Staphylococcus aureus, which is responsible for a high percentage of complications leading to high morbidity and mortality rates. The systemic inflammatory response syndrome (SIRS) criteria have been traditionally used to evaluate the presence of sepsis; however, recent evidence questions its predictive value due to its low sensitivity and specificity. In 2016, new criteria for sepsis were published and a new tool emerged, quick SOFA (qSOFA), for the rapid evaluation of infection in emergency services. OBJECTIVE: To compare the qSOFA and SRIS tools for the prediction of bacteremia caused by S. aureus. MATERIALS AND METHODS: We conducted an observational study in patients with S. aureus bacteremia to evaluate their phenotypic resistance patterns, some special features (sociodemographic characteristics, clinical and paraclinical values), complications, and mortality. The results of the qSOFA and SIRS scales were analyzed to identify which of them could better predict the presence of S. aureus bacteremia. RESULTS: Twenty-six bacteremic patients were identified. Staphylococcus aureus was the second most frequently isolated bacteria. The results evidenced a mortality rate of 50% (13 cases) and a prevalence of 30% of MRSA. For the clinical scores evaluated, the qSOFA scale was positive in 30.8% of the patients, and the SIRS scale, in 92.3%. DISCUSSION: The mortality rate for the population under study was high and the qSOFA tool had a lower diagnostic yield compared to the classic criteria for SIRS.
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spelling pubmed-74491002020-08-27 Comparación de la escala qSOFA para evaluar la falla orgánica secuencial y los criterios SIRS para sepsis a la cabecera de pacientes con bacteriemia por Staphylococcus aureus García, Óscar Álvarez, Tatiana Granados, Santiago Garzón, Vanessa González, Santiago Biomedica Artículo Original INTRODUCTION: One of the primary causes of community-acquired bacteremia also associated with nosocomial infections is Staphylococcus aureus, which is responsible for a high percentage of complications leading to high morbidity and mortality rates. The systemic inflammatory response syndrome (SIRS) criteria have been traditionally used to evaluate the presence of sepsis; however, recent evidence questions its predictive value due to its low sensitivity and specificity. In 2016, new criteria for sepsis were published and a new tool emerged, quick SOFA (qSOFA), for the rapid evaluation of infection in emergency services. OBJECTIVE: To compare the qSOFA and SRIS tools for the prediction of bacteremia caused by S. aureus. MATERIALS AND METHODS: We conducted an observational study in patients with S. aureus bacteremia to evaluate their phenotypic resistance patterns, some special features (sociodemographic characteristics, clinical and paraclinical values), complications, and mortality. The results of the qSOFA and SIRS scales were analyzed to identify which of them could better predict the presence of S. aureus bacteremia. RESULTS: Twenty-six bacteremic patients were identified. Staphylococcus aureus was the second most frequently isolated bacteria. The results evidenced a mortality rate of 50% (13 cases) and a prevalence of 30% of MRSA. For the clinical scores evaluated, the qSOFA scale was positive in 30.8% of the patients, and the SIRS scale, in 92.3%. DISCUSSION: The mortality rate for the population under study was high and the qSOFA tool had a lower diagnostic yield compared to the classic criteria for SIRS. Instituto Nacional de Salud 2020-08-20 /pmc/articles/PMC7449100/ /pubmed/32463614 http://dx.doi.org/10.7705/biomedica.4943 Text en https://creativecommons.org/licenses/by/4.0/ Este es un artículo publicado en acceso abierto bajo una licencia Creative Commons
spellingShingle Artículo Original
García, Óscar
Álvarez, Tatiana
Granados, Santiago
Garzón, Vanessa
González, Santiago
Comparación de la escala qSOFA para evaluar la falla orgánica secuencial y los criterios SIRS para sepsis a la cabecera de pacientes con bacteriemia por Staphylococcus aureus
title Comparación de la escala qSOFA para evaluar la falla orgánica secuencial y los criterios SIRS para sepsis a la cabecera de pacientes con bacteriemia por Staphylococcus aureus
title_full Comparación de la escala qSOFA para evaluar la falla orgánica secuencial y los criterios SIRS para sepsis a la cabecera de pacientes con bacteriemia por Staphylococcus aureus
title_fullStr Comparación de la escala qSOFA para evaluar la falla orgánica secuencial y los criterios SIRS para sepsis a la cabecera de pacientes con bacteriemia por Staphylococcus aureus
title_full_unstemmed Comparación de la escala qSOFA para evaluar la falla orgánica secuencial y los criterios SIRS para sepsis a la cabecera de pacientes con bacteriemia por Staphylococcus aureus
title_short Comparación de la escala qSOFA para evaluar la falla orgánica secuencial y los criterios SIRS para sepsis a la cabecera de pacientes con bacteriemia por Staphylococcus aureus
title_sort comparación de la escala qsofa para evaluar la falla orgánica secuencial y los criterios sirs para sepsis a la cabecera de pacientes con bacteriemia por staphylococcus aureus
topic Artículo Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449100/
https://www.ncbi.nlm.nih.gov/pubmed/32463614
http://dx.doi.org/10.7705/biomedica.4943
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