Computational Chemogenomics Drug Repositioning Strategy Enables the Discovery of Epirubicin as a New Repurposed Hit for Plasmodium falciparum and P. vivax

Widespread resistance against antimalarial drugs thwarts current efforts for controlling the disease and urges the discovery of new effective treatments. Drug repositioning is increasingly becoming an attractive strategy since it can reduce costs, risks, and time-to-market. Herein, we have used this...

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Detalles Bibliográficos
Autores principales: Ferreira, Letícia Tiburcio, Rodrigues, Juliana, Cassiano, Gustavo Capatti, Tavella, Tatyana Almeida, Tomaz, Kaira Cristina Peralis, Baia-da-Silva, Djane Clarys, Souza, Macejane Ferreira, Lima, Marilia Nunes do Nascimento, Mottin, Melina, Almeida, Ludimila Dias, Calit, Juliana, Puça, Maria Carolina Silva de Barros, Melo, Gisely Cardoso, Bargieri, Daniel Youssef, Lopes, Stefanie Costa Pinto, Lacerda, Marcus Vinicius Guimarães, Bilsland, Elizabeth, Sunnerhagen, Per, Neves, Bruno Junior, Andrade, Carolina Horta, Cravo, Pedro Vitor Lemos, Costa, Fabio Trindade Maranhão
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449180/
https://www.ncbi.nlm.nih.gov/pubmed/32601162
http://dx.doi.org/10.1128/AAC.02041-19

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