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How To Optimally Combine Genotypic and Phenotypic Drug Susceptibility Testing Methods for Pyrazinamide

False-susceptible phenotypic drug-susceptibility testing (DST) results for pyrazinamide due to mutations with MICs close to the critical concentration (CC) confound the classification of pncA resistance mutations, leading to an underestimate of the specificity of genotypic DST. This could be minimiz...

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Detalles Bibliográficos
Autores principales:	Köser, Claudio U., Cirillo, Daniela M., Miotto, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449218/ https://www.ncbi.nlm.nih.gov/pubmed/32571824 http://dx.doi.org/10.1128/AAC.01003-20

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