Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

BACKGROUND: Vaccines to prevent coronavirus disease 2019 (Covid-19) are urgently needed. The effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines on viral replication in both upper and lower airways is important to evaluate in nonhuman primates. METHODS: Nonhuman primates...

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Detalles Bibliográficos
Autores principales: Corbett, Kizzmekia S., Flynn, Barbara, Foulds, Kathryn E., Francica, Joseph R., Boyoglu-Barnum, Seyhan, Werner, Anne P., Flach, Britta, O’Connell, Sarah, Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Andersen, Hanne, Martinez, David R., Noe, Amy T., Douek, Naomi, Donaldson, Mitzi M., Nji, Nadesh N., Alvarado, Gabriela S., Edwards, Darin K., Flebbe, Dillon R., Lamb, Evan, Doria-Rose, Nicole A., Lin, Bob C., Louder, Mark K., O’Dell, Sijy, Schmidt, Stephen D., Phung, Emily, Chang, Lauren A., Yap, Christina, Todd, John-Paul M., Pessaint, Laurent, Van Ry, Alex, Browne, Shanai, Greenhouse, Jack, Putman-Taylor, Tammy, Strasbaugh, Amanda, Campbell, Tracey-Ann, Cook, Anthony, Dodson, Alan, Steingrebe, Katelyn, Shi, Wei, Zhang, Yi, Abiona, Olubukola M., Wang, Lingshu, Pegu, Amarendra, Yang, Eun Sung, Leung, Kwanyee, Zhou, Tongqing, Teng, I-Ting, Widge, Alicia, Gordon, Ingelise, Novik, Laura, Gillespie, Rebecca A., Loomis, Rebecca J., Moliva, Juan I., Stewart-Jones, Guillaume, Himansu, Sunny, Kong, Wing-Pui, Nason, Martha C., Morabito, Kaitlyn M., Ruckwardt, Tracy J., Ledgerwood, Julie E., Gaudinski, Martin R., Kwong, Peter D., Mascola, John R., Carfi, Andrea, Lewis, Mark G., Baric, Ralph S., McDermott, Adrian, Moore, Ian N., Sullivan, Nancy J., Roederer, Mario, Seder, Robert A., Graham, Barney S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Massachusetts Medical Society 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449230/
https://www.ncbi.nlm.nih.gov/pubmed/32722908
http://dx.doi.org/10.1056/NEJMoa2024671

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