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Natural HDAC‐1/8 inhibitor baicalein exerts therapeutic effect in CBF‐AML

BACKGROUND: Although targeting histone deacetylases (HDACs) may be an effective strategy for core binding factor‐acute myeloid leukemia (CBF‐AML) harboring t(8;21) or inv(16), HDAC inhibitors are reported to be limited by drug‐resistant characteristic. Our purpose is to evaluate the anti‐leukemia ef...

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Detalles Bibliográficos
Autores principales: Yu, Xiaoxuan, Li, Hui, Hu, Po, Qing, Yingjie, Wang, Xiangyuan, Zhu, Mengyuan, Wang, Hongzheng, Wang, Zhanyu, Xu, Jingyan, Guo, Qinglong, Hui, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449246/
https://www.ncbi.nlm.nih.gov/pubmed/32898337
http://dx.doi.org/10.1002/ctm2.154

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