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A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction
AIMS: Genome-wide association studies (GWAS) have consistently identified an association between coronary artery disease (CAD) and a locus on chromosome 10 containing a single gene, JCAD (formerly KIAA1462). However, little is known about the mechanism by which JCAD could influence the development o...
Autores principales: | Douglas, Gillian, Mehta, Vedanta, Al Haj Zen, Ayman, Akoumianakis, Ioannis, Goel, Anuj, Rashbrook, Victoria S, Trelfa, Lucy, Donovan, Lucy, Drydale, Edward, Chuaiphichai, Surawee, Antoniades, Charalambos, Watkins, Hugh, Kyriakou, Theodosios, Tzima, Ellie, Channon, Keith M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449560/ https://www.ncbi.nlm.nih.gov/pubmed/31584065 http://dx.doi.org/10.1093/cvr/cvz263 |
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