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Stationary distribution and extinction of a stochastic staged progression AIDS model with staged treatment and second-order perturbation

Focusing on deterministic AIDS model proposed by Hyman (2000) and the detailed data from the World Health Organization (WHO), there are three stages of AIDS process which are described as Acute infection period, Asymptomatic phase and AIDS stage. Our paper is therefore concerned with a stochastic st...

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Autores principales: Han, Bingtao, Jiang, Daqing, Hayat, Tasawar, Alsaedi, Ahmed, Ahmad, Bashir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449666/
https://www.ncbi.nlm.nih.gov/pubmed/32868968
http://dx.doi.org/10.1016/j.chaos.2020.110238
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author Han, Bingtao
Jiang, Daqing
Hayat, Tasawar
Alsaedi, Ahmed
Ahmad, Bashir
author_facet Han, Bingtao
Jiang, Daqing
Hayat, Tasawar
Alsaedi, Ahmed
Ahmad, Bashir
author_sort Han, Bingtao
collection PubMed
description Focusing on deterministic AIDS model proposed by Hyman (2000) and the detailed data from the World Health Organization (WHO), there are three stages of AIDS process which are described as Acute infection period, Asymptomatic phase and AIDS stage. Our paper is therefore concerned with a stochastic staged progression AIDS model with staged treatment. In view of the complexity of random disturbances, we reasonably take second-order perturbation into consideration for realistic sense. By means of our creative transformation technique and stochastic Lyapunov method, a critical value [Formula: see text] is firstly obtained for the existence and uniqueness of ergodic stationary distribution to the stochastic system. Not only does it respectively reveal the corresponding dynamical effects of the linear and second-order perturbations to the model, but the unified form of second-order and linear fluctuations is derived. Next, some sufficient conditions about extinction of stochastic system are established in view of the basic reproduction number [Formula: see text]. Finally, some examples and numerical simulations are introduced to illustrate our analytical results. In addition, some advantages of our new method and theory are highlighted by comparison with other existing results at the end of this paper.
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spelling pubmed-74496662020-08-27 Stationary distribution and extinction of a stochastic staged progression AIDS model with staged treatment and second-order perturbation Han, Bingtao Jiang, Daqing Hayat, Tasawar Alsaedi, Ahmed Ahmad, Bashir Chaos Solitons Fractals Article Focusing on deterministic AIDS model proposed by Hyman (2000) and the detailed data from the World Health Organization (WHO), there are three stages of AIDS process which are described as Acute infection period, Asymptomatic phase and AIDS stage. Our paper is therefore concerned with a stochastic staged progression AIDS model with staged treatment. In view of the complexity of random disturbances, we reasonably take second-order perturbation into consideration for realistic sense. By means of our creative transformation technique and stochastic Lyapunov method, a critical value [Formula: see text] is firstly obtained for the existence and uniqueness of ergodic stationary distribution to the stochastic system. Not only does it respectively reveal the corresponding dynamical effects of the linear and second-order perturbations to the model, but the unified form of second-order and linear fluctuations is derived. Next, some sufficient conditions about extinction of stochastic system are established in view of the basic reproduction number [Formula: see text]. Finally, some examples and numerical simulations are introduced to illustrate our analytical results. In addition, some advantages of our new method and theory are highlighted by comparison with other existing results at the end of this paper. Published by Elsevier Ltd. 2020-11 2020-08-26 /pmc/articles/PMC7449666/ /pubmed/32868968 http://dx.doi.org/10.1016/j.chaos.2020.110238 Text en © 2020 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Han, Bingtao
Jiang, Daqing
Hayat, Tasawar
Alsaedi, Ahmed
Ahmad, Bashir
Stationary distribution and extinction of a stochastic staged progression AIDS model with staged treatment and second-order perturbation
title Stationary distribution and extinction of a stochastic staged progression AIDS model with staged treatment and second-order perturbation
title_full Stationary distribution and extinction of a stochastic staged progression AIDS model with staged treatment and second-order perturbation
title_fullStr Stationary distribution and extinction of a stochastic staged progression AIDS model with staged treatment and second-order perturbation
title_full_unstemmed Stationary distribution and extinction of a stochastic staged progression AIDS model with staged treatment and second-order perturbation
title_short Stationary distribution and extinction of a stochastic staged progression AIDS model with staged treatment and second-order perturbation
title_sort stationary distribution and extinction of a stochastic staged progression aids model with staged treatment and second-order perturbation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449666/
https://www.ncbi.nlm.nih.gov/pubmed/32868968
http://dx.doi.org/10.1016/j.chaos.2020.110238
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