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HI-511 overcomes melanoma drug resistance via targeting AURKB and BRAF V600E
Rationale: Melanoma is an aggressive tumor of the skin and drug resistance is still a major problem in melanoma therapy. Novel targets and effective agents to overcome drug resistant melanoma are urgently needed in clinical therapy. Methods: Gene Expression Omnibus (GEO) database analysis, pathway e...
Autores principales: | Chang, Xiaoyu, Zhang, Tianshun, Wang, Qiushi, Rathore, Moeez Ghani, Reddy, Kanamata, Chen, Hanyong, Shin, Seung Ho, Ma, Wei-ya, Bode, Ann M, Dong, Zigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449901/ https://www.ncbi.nlm.nih.gov/pubmed/32863956 http://dx.doi.org/10.7150/thno.44342 |
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