Inter‐individual and inter‐regional variations in enteric drug metabolizing enzyme activities: Results with cryopreserved human intestinal mucosal epithelia (CHIM) from the small intestines of 14 donors

We have previously reported successful isolation and cryopreservation of human intestinal mucosa (CHIM) with retention of viability and drug metabolizing enzyme activities. Here we report the results of the quantification of drug metabolizing enzyme activities in CHIM from different regions of the s...

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Detalles Bibliográficos
Autores principales: Li, Albert P., Ho, Ming‐Chih D., Alam, Novera, Mitchell, Walter, Wong, Susan, Yan, Zhengyin, Kenny, Jane R., E. C. A. Hop, Cornelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449955/
https://www.ncbi.nlm.nih.gov/pubmed/32851819
http://dx.doi.org/10.1002/prp2.645

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