Cargando…

Efficient numerical computation of the basic reproduction number for structured populations

As widely known, the basic reproduction number plays a key role in weighing birth/infection and death/recovery processes in several models of population dynamics. In this general setting, its characterization as the spectral radius of next generation operators is rather elegant, but simultaneously p...

Descripción completa

Detalles Bibliográficos
Autores principales: Breda, Dimitri, Florian, Francesco, Ripoll, Jordi, Vermiglio, Rossana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449967/
https://www.ncbi.nlm.nih.gov/pubmed/32868963
http://dx.doi.org/10.1016/j.cam.2020.113165
_version_ 1783574729848782848
author Breda, Dimitri
Florian, Francesco
Ripoll, Jordi
Vermiglio, Rossana
author_facet Breda, Dimitri
Florian, Francesco
Ripoll, Jordi
Vermiglio, Rossana
author_sort Breda, Dimitri
collection PubMed
description As widely known, the basic reproduction number plays a key role in weighing birth/infection and death/recovery processes in several models of population dynamics. In this general setting, its characterization as the spectral radius of next generation operators is rather elegant, but simultaneously poses serious obstacles to its practical determination. In this work we address the problem numerically by reducing the relevant operators to matrices through a pseudospectral collocation, eventually computing the sought quantity by solving finite-dimensional eigenvalue problems. The approach is illustrated for two classes of models, respectively from ecology and epidemiology. Several numerical tests demonstrate experimentally important features of the method, like fast convergence and influence of the smoothness of the models’ coefficients. Examples of robust analysis of instances of specific models are also presented to show potentialities and ease of application.
format Online
Article
Text
id pubmed-7449967
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-74499672020-08-27 Efficient numerical computation of the basic reproduction number for structured populations Breda, Dimitri Florian, Francesco Ripoll, Jordi Vermiglio, Rossana J Comput Appl Math Article As widely known, the basic reproduction number plays a key role in weighing birth/infection and death/recovery processes in several models of population dynamics. In this general setting, its characterization as the spectral radius of next generation operators is rather elegant, but simultaneously poses serious obstacles to its practical determination. In this work we address the problem numerically by reducing the relevant operators to matrices through a pseudospectral collocation, eventually computing the sought quantity by solving finite-dimensional eigenvalue problems. The approach is illustrated for two classes of models, respectively from ecology and epidemiology. Several numerical tests demonstrate experimentally important features of the method, like fast convergence and influence of the smoothness of the models’ coefficients. Examples of robust analysis of instances of specific models are also presented to show potentialities and ease of application. Elsevier B.V. 2021-03-01 2020-08-27 /pmc/articles/PMC7449967/ /pubmed/32868963 http://dx.doi.org/10.1016/j.cam.2020.113165 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Breda, Dimitri
Florian, Francesco
Ripoll, Jordi
Vermiglio, Rossana
Efficient numerical computation of the basic reproduction number for structured populations
title Efficient numerical computation of the basic reproduction number for structured populations
title_full Efficient numerical computation of the basic reproduction number for structured populations
title_fullStr Efficient numerical computation of the basic reproduction number for structured populations
title_full_unstemmed Efficient numerical computation of the basic reproduction number for structured populations
title_short Efficient numerical computation of the basic reproduction number for structured populations
title_sort efficient numerical computation of the basic reproduction number for structured populations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449967/
https://www.ncbi.nlm.nih.gov/pubmed/32868963
http://dx.doi.org/10.1016/j.cam.2020.113165
work_keys_str_mv AT bredadimitri efficientnumericalcomputationofthebasicreproductionnumberforstructuredpopulations
AT florianfrancesco efficientnumericalcomputationofthebasicreproductionnumberforstructuredpopulations
AT ripolljordi efficientnumericalcomputationofthebasicreproductionnumberforstructuredpopulations
AT vermigliorossana efficientnumericalcomputationofthebasicreproductionnumberforstructuredpopulations