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Tubeimoside I-induced lung cancer cell death and the underlying crosstalk between lysosomes and mitochondria
Cancer cells have developed chemoresistance and have improved their survival through the upregulation of autophagic mechanisms that protect mitochondrial function. Here, we report that the traditional Chinese anticancer agent tubeimoside I (Tub), which is a potent inhibitor of autophagy, can promote...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449972/ https://www.ncbi.nlm.nih.gov/pubmed/32848130 http://dx.doi.org/10.1038/s41419-020-02915-x |