Cargando…
Tubeimoside I-induced lung cancer cell death and the underlying crosstalk between lysosomes and mitochondria
Cancer cells have developed chemoresistance and have improved their survival through the upregulation of autophagic mechanisms that protect mitochondrial function. Here, we report that the traditional Chinese anticancer agent tubeimoside I (Tub), which is a potent inhibitor of autophagy, can promote...
Autores principales: | Wang, Kun, Zhan, Yujuan, Chen, Bonan, Lu, Yuhua, Yin, Ting, Zhou, Shikun, Zhang, Weibin, Liu, Xiaodong, Du, Biaoyan, Wei, Xianli, Xiao, Jianyong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449972/ https://www.ncbi.nlm.nih.gov/pubmed/32848130 http://dx.doi.org/10.1038/s41419-020-02915-x |
Ejemplares similares
-
Blockage of Autophagic Flux and Induction of Mitochondria Fragmentation by Paroxetine Hydrochloride in Lung Cancer Cells Promotes Apoptosis via the ROS-MAPK Pathway
por: Wang, Kun, et al.
Publicado: (2020) -
N-Methylparoxetine Blocked Autophagic Flux and Induced Apoptosis by Activating ROS-MAPK Pathway in Non-Small Cell Lung Cancer Cells
por: Wang, Kun, et al.
Publicado: (2019) -
Crosstalk between Lysosomes and Mitochondria in Parkinson's Disease
por: Plotegher, Nicoletta, et al.
Publicado: (2017) -
Dioscin Inhibits the Invasion and Migration of Hepatocellular Carcinoma HepG2 Cells by Reversing TGF-β1-Induced Epithelial-Mesenchymal Transition
por: Chen, Bonan, et al.
Publicado: (2019) -
The Novel Autophagy Inhibitor Alpha-Hederin Promoted Paclitaxel Cytotoxicity by Increasing Reactive Oxygen Species Accumulation in Non-Small Cell Lung Cancer Cells
por: Zhan, Yujuan, et al.
Publicado: (2018)