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Methyl-CpG-binding protein 2 drives the Furin/TGF-β1/Smad axis to promote epithelial–mesenchymal transition in pancreatic cancer cells

Methyl-CpG-binding protein 2 (MeCP2) has been characterized as an oncogene in several types of cancer. However, its precise role in pancreatic ductal adenocarcinoma (PDAC) remains unclear. Hence, this study aimed to evaluate the potential role of MeCP2 in pancreatic cancer progression. We found that...

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Detalles Bibliográficos
Autores principales:	Wang, Huizhi, Li, Jie, He, Junbo, Liu, Yawen, Feng, Wen, Zhou, Hailang, Zhou, Meng, Wei, Hong, Lu, Ying, Peng, Wanxin, Du, Fengyi, Gong, Aihua, Xu, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450052/ https://www.ncbi.nlm.nih.gov/pubmed/32848128 http://dx.doi.org/10.1038/s41389-020-00258-y

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