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The folding and unfolding behavior of ribonuclease H on the ribosome
The health of a cell depends on accurate translation and proper protein folding, whereas misfolding can lead to aggregation and disease. The first opportunity for a protein to fold occurs during translation, when the ribosome and surrounding environment can affect the nascent chain energy landscape....
Autores principales: | Jensen, Madeleine K., Samelson, Avi J., Steward, Annette, Clarke, Jane, Marqusee, Susan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450101/ https://www.ncbi.nlm.nih.gov/pubmed/32527724 http://dx.doi.org/10.1074/jbc.RA120.013909 |
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