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An astrocyte cell line that differentially propagates murine prions
Prion diseases are fatal infectious neurodegenerative disorders in human and animals caused by misfolding of the cellular prion protein (PrP(C)) into the pathological isoform PrP(Sc). Elucidating the molecular and cellular mechanisms underlying prion propagation may help to develop disease intervent...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450132/ https://www.ncbi.nlm.nih.gov/pubmed/32561641 http://dx.doi.org/10.1074/jbc.RA120.012596 |