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An astrocyte cell line that differentially propagates murine prions

Prion diseases are fatal infectious neurodegenerative disorders in human and animals caused by misfolding of the cellular prion protein (PrP(C)) into the pathological isoform PrP(Sc). Elucidating the molecular and cellular mechanisms underlying prion propagation may help to develop disease intervent...

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Detalles Bibliográficos
Autores principales:	Tahir, Waqas, Abdulrahman, Basant, Abdelaziz, Dalia H., Thapa, Simrika, Walia, Rupali, Schätzl, Hermann M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450132/ https://www.ncbi.nlm.nih.gov/pubmed/32561641 http://dx.doi.org/10.1074/jbc.RA120.012596

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