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Comprehensive elaboration of the cGAS-STING signaling axis in cancer development and immunotherapy

Cellular recognition of microbial DNA is an evolutionarily conserved mechanism by which the innate immune system detects pathogens. Cyclic GMP-AMP synthase (cGAS) and its downstream effector, stimulator of interferon genes (STING), are involved in mediating fundamental innate antimicrobial immunity...

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Detalles Bibliográficos
Autores principales:	Zheng, Juyan, Mo, Junluan, Zhu, Tao, Zhuo, Wei, Yi, Yueneng, Hu, Shuo, Yin, Jiye, Zhang, Wei, Zhou, Honghao, Liu, Zhaoqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450153/ https://www.ncbi.nlm.nih.gov/pubmed/32854711 http://dx.doi.org/10.1186/s12943-020-01250-1

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