Cargando…
2019 novel coronavirus (COVID-19) pneumonia: CT manifestations and pattern of evolution in 110 patients in Jiangxi, China
OBJECTIVES: To elucidate the CT manifestations and patterns of evolution in patients with COVID-19 pneumonia. METHODS: This is a retrospective review of CT scans of 110 patients. All 110 patients had initial and second CT scans, 60 of 110 patients had three serial CT scans, and 17 of 60 patients had...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450162/ https://www.ncbi.nlm.nih.gov/pubmed/32852587 http://dx.doi.org/10.1007/s00330-020-07201-0 |
_version_ | 1783574759898873856 |
---|---|
author | Zhan, Jie Li, Haijun Yu, Honghui Liu, Xiaochen Zeng, Xianjun Peng, Dechang Zhang, Wei |
author_facet | Zhan, Jie Li, Haijun Yu, Honghui Liu, Xiaochen Zeng, Xianjun Peng, Dechang Zhang, Wei |
author_sort | Zhan, Jie |
collection | PubMed |
description | OBJECTIVES: To elucidate the CT manifestations and patterns of evolution in patients with COVID-19 pneumonia. METHODS: This is a retrospective review of CT scans of 110 patients. All 110 patients had initial and second CT scans, 60 of 110 patients had three serial CT scans, and 17 of 60 patients had four serial CT scans. Numerous characteristics of pulmonary and extrapulmonary abnormalities and recognizable patterns of evolution were evaluated. RESULTS: Of the 110 initial CT scans, ground-glass opacities without consolidation (65.4%) were more common than a consolidation or mixed pattern. The most common findings were subpleural involvement (77.2%), multifocal involvement (80.7%), and bilateral involvement (67.3%). Three serial CT scans of 60 patients showed four patterns of CT evolution: type 1 showing relatively high CT scores on initial CT (averaged 4 days after symptom onset), with mild progression and improvement on follow-up CT scans (25%); type 2 with progression of CT findings from initial CT to first follow-up CT (averaged 9 days after symptom onset) with subsequent improvement on second follow-up CT (averaged 13 days after symptom onset, 61.7%); type 3 with no CT changes (5.0%); and type 4 pattern was similar to type 2 but with a more prolonged course and more severe CT findings (8.3%). CONCLUSIONS: Predominant findings at initial CT scans were bilateral multifocal subpleural GGO. The most commonly shown evolution pattern was type 2: progression of disease with increased extent and density of opacities on first follow-up CT followed by improvement on second follow-up CT. KEY POINTS: • Predominant findings at initial CT in patients with COVID-19 infection are bilateral multifocal subpleural ground-glass opacities. • Ill-defined patchy or nodular opacities were most commonly observed on CT scans with the right lower lobe most commonly involved. • The most commonly shown evolution pattern on chest CT was type 2: progression of CT findings from initial CT to first follow-up CT with subsequent improvement on second follow-up CT. |
format | Online Article Text |
id | pubmed-7450162 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-74501622020-08-27 2019 novel coronavirus (COVID-19) pneumonia: CT manifestations and pattern of evolution in 110 patients in Jiangxi, China Zhan, Jie Li, Haijun Yu, Honghui Liu, Xiaochen Zeng, Xianjun Peng, Dechang Zhang, Wei Eur Radiol Chest OBJECTIVES: To elucidate the CT manifestations and patterns of evolution in patients with COVID-19 pneumonia. METHODS: This is a retrospective review of CT scans of 110 patients. All 110 patients had initial and second CT scans, 60 of 110 patients had three serial CT scans, and 17 of 60 patients had four serial CT scans. Numerous characteristics of pulmonary and extrapulmonary abnormalities and recognizable patterns of evolution were evaluated. RESULTS: Of the 110 initial CT scans, ground-glass opacities without consolidation (65.4%) were more common than a consolidation or mixed pattern. The most common findings were subpleural involvement (77.2%), multifocal involvement (80.7%), and bilateral involvement (67.3%). Three serial CT scans of 60 patients showed four patterns of CT evolution: type 1 showing relatively high CT scores on initial CT (averaged 4 days after symptom onset), with mild progression and improvement on follow-up CT scans (25%); type 2 with progression of CT findings from initial CT to first follow-up CT (averaged 9 days after symptom onset) with subsequent improvement on second follow-up CT (averaged 13 days after symptom onset, 61.7%); type 3 with no CT changes (5.0%); and type 4 pattern was similar to type 2 but with a more prolonged course and more severe CT findings (8.3%). CONCLUSIONS: Predominant findings at initial CT scans were bilateral multifocal subpleural GGO. The most commonly shown evolution pattern was type 2: progression of disease with increased extent and density of opacities on first follow-up CT followed by improvement on second follow-up CT. KEY POINTS: • Predominant findings at initial CT in patients with COVID-19 infection are bilateral multifocal subpleural ground-glass opacities. • Ill-defined patchy or nodular opacities were most commonly observed on CT scans with the right lower lobe most commonly involved. • The most commonly shown evolution pattern on chest CT was type 2: progression of CT findings from initial CT to first follow-up CT with subsequent improvement on second follow-up CT. Springer Berlin Heidelberg 2020-08-27 2021 /pmc/articles/PMC7450162/ /pubmed/32852587 http://dx.doi.org/10.1007/s00330-020-07201-0 Text en © European Society of Radiology 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Chest Zhan, Jie Li, Haijun Yu, Honghui Liu, Xiaochen Zeng, Xianjun Peng, Dechang Zhang, Wei 2019 novel coronavirus (COVID-19) pneumonia: CT manifestations and pattern of evolution in 110 patients in Jiangxi, China |
title | 2019 novel coronavirus (COVID-19) pneumonia: CT manifestations and pattern of evolution in 110 patients in Jiangxi, China |
title_full | 2019 novel coronavirus (COVID-19) pneumonia: CT manifestations and pattern of evolution in 110 patients in Jiangxi, China |
title_fullStr | 2019 novel coronavirus (COVID-19) pneumonia: CT manifestations and pattern of evolution in 110 patients in Jiangxi, China |
title_full_unstemmed | 2019 novel coronavirus (COVID-19) pneumonia: CT manifestations and pattern of evolution in 110 patients in Jiangxi, China |
title_short | 2019 novel coronavirus (COVID-19) pneumonia: CT manifestations and pattern of evolution in 110 patients in Jiangxi, China |
title_sort | 2019 novel coronavirus (covid-19) pneumonia: ct manifestations and pattern of evolution in 110 patients in jiangxi, china |
topic | Chest |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450162/ https://www.ncbi.nlm.nih.gov/pubmed/32852587 http://dx.doi.org/10.1007/s00330-020-07201-0 |
work_keys_str_mv | AT zhanjie 2019novelcoronaviruscovid19pneumoniactmanifestationsandpatternofevolutionin110patientsinjiangxichina AT lihaijun 2019novelcoronaviruscovid19pneumoniactmanifestationsandpatternofevolutionin110patientsinjiangxichina AT yuhonghui 2019novelcoronaviruscovid19pneumoniactmanifestationsandpatternofevolutionin110patientsinjiangxichina AT liuxiaochen 2019novelcoronaviruscovid19pneumoniactmanifestationsandpatternofevolutionin110patientsinjiangxichina AT zengxianjun 2019novelcoronaviruscovid19pneumoniactmanifestationsandpatternofevolutionin110patientsinjiangxichina AT pengdechang 2019novelcoronaviruscovid19pneumoniactmanifestationsandpatternofevolutionin110patientsinjiangxichina AT zhangwei 2019novelcoronaviruscovid19pneumoniactmanifestationsandpatternofevolutionin110patientsinjiangxichina |