Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture

Microglial inflammation driven by the NACHT, LRR and PYD domain‐containing protein 3 (NLRP3) inflammasome contributes to brain disease and is a therapeutic target. Most mechanistic studies on NLRP3 activation use two‐dimensional pure microglial cell culture systems. Here we studied the activation of...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoyle, Christopher, Redondo‐Castro, Elena, Cook, James, Tzeng, Te‐Chen, Allan, Stuart M., Brough, David, Lemarchand, Eloise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450173/
https://www.ncbi.nlm.nih.gov/pubmed/32445196
http://dx.doi.org/10.1111/imm.13221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450173/
https://www.ncbi.nlm.nih.gov/pubmed/32445196
http://dx.doi.org/10.1111/imm.13221

Ejemplares similares