Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture

Microglial inflammation driven by the NACHT, LRR and PYD domain‐containing protein 3 (NLRP3) inflammasome contributes to brain disease and is a therapeutic target. Most mechanistic studies on NLRP3 activation use two‐dimensional pure microglial cell culture systems. Here we studied the activation of...

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Detalhes bibliográficos
Principais autores: Hoyle, Christopher, Redondo‐Castro, Elena, Cook, James, Tzeng, Te‐Chen, Allan, Stuart M., Brough, David, Lemarchand, Eloise
Formato: Online Atigo Texto
Idioma:English
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450173/
https://www.ncbi.nlm.nih.gov/pubmed/32445196
http://dx.doi.org/10.1111/imm.13221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450173/
https://www.ncbi.nlm.nih.gov/pubmed/32445196
http://dx.doi.org/10.1111/imm.13221

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