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Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture

Microglial inflammation driven by the NACHT, LRR and PYD domain‐containing protein 3 (NLRP3) inflammasome contributes to brain disease and is a therapeutic target. Most mechanistic studies on NLRP3 activation use two‐dimensional pure microglial cell culture systems. Here we studied the activation of...

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Detalles Bibliográficos
Autores principales:	Hoyle, Christopher, Redondo‐Castro, Elena, Cook, James, Tzeng, Te‐Chen, Allan, Stuart M., Brough, David, Lemarchand, Eloise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450173/ https://www.ncbi.nlm.nih.gov/pubmed/32445196 http://dx.doi.org/10.1111/imm.13221

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