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Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture
Microglial inflammation driven by the NACHT, LRR and PYD domain‐containing protein 3 (NLRP3) inflammasome contributes to brain disease and is a therapeutic target. Most mechanistic studies on NLRP3 activation use two‐dimensional pure microglial cell culture systems. Here we studied the activation of...
Autors principals: | , , , , , , |
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Format: | Online Article Text |
Idioma: | English |
Publicat: |
John Wiley and Sons Inc.
2020
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Matèries: | |
Accés en línia: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450173/ https://www.ncbi.nlm.nih.gov/pubmed/32445196 http://dx.doi.org/10.1111/imm.13221 |