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Extracorporeal membrane oxygenation as a bridge to lung transplantation in a Turkish lung transplantation program: our initial experience

Lung transplantation is a life-saving treatment for patients with end-stage lung disease. Although the number of lung transplants has increased over the years, the number of available donor lungs has not increased at the same rate, leading to the death of transplant candidates on waiting lists. In t...

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Autores principales: Vayvada, Mustafa, Uygun, Yesim, Cıtak, Sevinc, Sarıbas, Ertan, Erkılıc, Atakan, Tasci, Erdal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450232/
https://www.ncbi.nlm.nih.gov/pubmed/32852668
http://dx.doi.org/10.1007/s10047-020-01204-w
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author Vayvada, Mustafa
Uygun, Yesim
Cıtak, Sevinc
Sarıbas, Ertan
Erkılıc, Atakan
Tasci, Erdal
author_facet Vayvada, Mustafa
Uygun, Yesim
Cıtak, Sevinc
Sarıbas, Ertan
Erkılıc, Atakan
Tasci, Erdal
author_sort Vayvada, Mustafa
collection PubMed
description Lung transplantation is a life-saving treatment for patients with end-stage lung disease. Although the number of lung transplants has increased over the years, the number of available donor lungs has not increased at the same rate, leading to the death of transplant candidates on waiting lists. In this paper, we presented our initial experience with the use of extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation. Between December 2016 and August 2018, we retrospectively reviewed the use of ECMO as a bridge to lung transplantation. Thirteen patients underwent preparative ECMO for bridging to lung transplantation, and seven patients successfully underwent bridging to lung transplantation. The average age of the patients was 45.7 years (range, 19–62 years). The ECMO support period lasted 3–55 days (mean, 18.7 days; median, 13 days). In seven patients, bridging to lung transplantation was performed successfully. The mean age of patients was 49.8 years (range 42–62). Bridging time was 3–55 days (mean, 19 days; median, 13 days). Two patients died in the early postoperative period. Five patients survived until discharge from the hospital. One-year survival was achieved in four patients. ECMO can be used safely for a long time to meet the physiological needs of critically ill patients. The use of ECMO as a bridge to lung transplantation is an acceptable treatment option to reduce the number of deaths on the waiting list. Despite the successful results achieved, this approach still involves risks and complications.
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spelling pubmed-74502322020-08-27 Extracorporeal membrane oxygenation as a bridge to lung transplantation in a Turkish lung transplantation program: our initial experience Vayvada, Mustafa Uygun, Yesim Cıtak, Sevinc Sarıbas, Ertan Erkılıc, Atakan Tasci, Erdal J Artif Organs Original Article Lung transplantation is a life-saving treatment for patients with end-stage lung disease. Although the number of lung transplants has increased over the years, the number of available donor lungs has not increased at the same rate, leading to the death of transplant candidates on waiting lists. In this paper, we presented our initial experience with the use of extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation. Between December 2016 and August 2018, we retrospectively reviewed the use of ECMO as a bridge to lung transplantation. Thirteen patients underwent preparative ECMO for bridging to lung transplantation, and seven patients successfully underwent bridging to lung transplantation. The average age of the patients was 45.7 years (range, 19–62 years). The ECMO support period lasted 3–55 days (mean, 18.7 days; median, 13 days). In seven patients, bridging to lung transplantation was performed successfully. The mean age of patients was 49.8 years (range 42–62). Bridging time was 3–55 days (mean, 19 days; median, 13 days). Two patients died in the early postoperative period. Five patients survived until discharge from the hospital. One-year survival was achieved in four patients. ECMO can be used safely for a long time to meet the physiological needs of critically ill patients. The use of ECMO as a bridge to lung transplantation is an acceptable treatment option to reduce the number of deaths on the waiting list. Despite the successful results achieved, this approach still involves risks and complications. Springer Japan 2020-08-27 2021 /pmc/articles/PMC7450232/ /pubmed/32852668 http://dx.doi.org/10.1007/s10047-020-01204-w Text en © The Japanese Society for Artificial Organs 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Article
Vayvada, Mustafa
Uygun, Yesim
Cıtak, Sevinc
Sarıbas, Ertan
Erkılıc, Atakan
Tasci, Erdal
Extracorporeal membrane oxygenation as a bridge to lung transplantation in a Turkish lung transplantation program: our initial experience
title Extracorporeal membrane oxygenation as a bridge to lung transplantation in a Turkish lung transplantation program: our initial experience
title_full Extracorporeal membrane oxygenation as a bridge to lung transplantation in a Turkish lung transplantation program: our initial experience
title_fullStr Extracorporeal membrane oxygenation as a bridge to lung transplantation in a Turkish lung transplantation program: our initial experience
title_full_unstemmed Extracorporeal membrane oxygenation as a bridge to lung transplantation in a Turkish lung transplantation program: our initial experience
title_short Extracorporeal membrane oxygenation as a bridge to lung transplantation in a Turkish lung transplantation program: our initial experience
title_sort extracorporeal membrane oxygenation as a bridge to lung transplantation in a turkish lung transplantation program: our initial experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450232/
https://www.ncbi.nlm.nih.gov/pubmed/32852668
http://dx.doi.org/10.1007/s10047-020-01204-w
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