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Convalescent plasma as a treatment modality for coronavirus disease 2019 in Sudan
Coronavirus disease 2019 (COVID-19) is a disease spreading rapidly in Sudan, the rest of the African continent and the world with no known definitive treatment or vaccines. However, among many treatment interventions being tested globally, beneficial effects and clinical improvements have been repor...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450236/ https://www.ncbi.nlm.nih.gov/pubmed/32900597 http://dx.doi.org/10.1016/j.transci.2020.102918 |
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author | Hassan, Mozan Osman Osman, Asma Ahmed Elbasit, Hana Elsir Abd Hassan, Hanan Elsamani Rufai, Hala Satti, Maria M.M. Elnegoumi, Musab Idris, Roaa Musa, Ashraf Ali, Abdelhakam H. Zroog, Susan Ali Altayb, Abduelbagi D.A. Khairy, Amna Allam, Mushal Abdelhalim, Asaad Tageldein Idris |
author_facet | Hassan, Mozan Osman Osman, Asma Ahmed Elbasit, Hana Elsir Abd Hassan, Hanan Elsamani Rufai, Hala Satti, Maria M.M. Elnegoumi, Musab Idris, Roaa Musa, Ashraf Ali, Abdelhakam H. Zroog, Susan Ali Altayb, Abduelbagi D.A. Khairy, Amna Allam, Mushal Abdelhalim, Asaad Tageldein Idris |
author_sort | Hassan, Mozan Osman |
collection | PubMed |
description | Coronavirus disease 2019 (COVID-19) is a disease spreading rapidly in Sudan, the rest of the African continent and the world with no known definitive treatment or vaccines. However, among many treatment interventions being tested globally, beneficial effects and clinical improvements have been reported when convalescent plasma is used for treating COVID-19 patients. We prepared a guiding protocol for treating early to moderate COVID-19 patients with plasma transfusion from convalescent COVID-19 patients. This protocol was deduced based on previously published reports and studies that evaluated and tested convalescent plasma as a prospective therapy for COVID-19 patients. The protocol covers instructions on patient and donor selection criteria, plasma harvesting, plasma product specifications, dosage and precautions for convalescent plasma collection and transfusion process. Altogether, we prepared a treatment protocol that is tailored to the context of Sudan to be adopted by Sudan's health authority. Moreover, it will also provide reference for researchers to design open label clinical trials for convalescent plasma transfusion. |
format | Online Article Text |
id | pubmed-7450236 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-74502362020-08-27 Convalescent plasma as a treatment modality for coronavirus disease 2019 in Sudan Hassan, Mozan Osman Osman, Asma Ahmed Elbasit, Hana Elsir Abd Hassan, Hanan Elsamani Rufai, Hala Satti, Maria M.M. Elnegoumi, Musab Idris, Roaa Musa, Ashraf Ali, Abdelhakam H. Zroog, Susan Ali Altayb, Abduelbagi D.A. Khairy, Amna Allam, Mushal Abdelhalim, Asaad Tageldein Idris Transfus Apher Sci Article Coronavirus disease 2019 (COVID-19) is a disease spreading rapidly in Sudan, the rest of the African continent and the world with no known definitive treatment or vaccines. However, among many treatment interventions being tested globally, beneficial effects and clinical improvements have been reported when convalescent plasma is used for treating COVID-19 patients. We prepared a guiding protocol for treating early to moderate COVID-19 patients with plasma transfusion from convalescent COVID-19 patients. This protocol was deduced based on previously published reports and studies that evaluated and tested convalescent plasma as a prospective therapy for COVID-19 patients. The protocol covers instructions on patient and donor selection criteria, plasma harvesting, plasma product specifications, dosage and precautions for convalescent plasma collection and transfusion process. Altogether, we prepared a treatment protocol that is tailored to the context of Sudan to be adopted by Sudan's health authority. Moreover, it will also provide reference for researchers to design open label clinical trials for convalescent plasma transfusion. Elsevier Ltd. 2020-12 2020-08-27 /pmc/articles/PMC7450236/ /pubmed/32900597 http://dx.doi.org/10.1016/j.transci.2020.102918 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Hassan, Mozan Osman Osman, Asma Ahmed Elbasit, Hana Elsir Abd Hassan, Hanan Elsamani Rufai, Hala Satti, Maria M.M. Elnegoumi, Musab Idris, Roaa Musa, Ashraf Ali, Abdelhakam H. Zroog, Susan Ali Altayb, Abduelbagi D.A. Khairy, Amna Allam, Mushal Abdelhalim, Asaad Tageldein Idris Convalescent plasma as a treatment modality for coronavirus disease 2019 in Sudan |
title | Convalescent plasma as a treatment modality for coronavirus disease 2019 in Sudan |
title_full | Convalescent plasma as a treatment modality for coronavirus disease 2019 in Sudan |
title_fullStr | Convalescent plasma as a treatment modality for coronavirus disease 2019 in Sudan |
title_full_unstemmed | Convalescent plasma as a treatment modality for coronavirus disease 2019 in Sudan |
title_short | Convalescent plasma as a treatment modality for coronavirus disease 2019 in Sudan |
title_sort | convalescent plasma as a treatment modality for coronavirus disease 2019 in sudan |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450236/ https://www.ncbi.nlm.nih.gov/pubmed/32900597 http://dx.doi.org/10.1016/j.transci.2020.102918 |
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