IL-6 −572C>G and CARD8 304T>A Genetic Polymorphisms are Associated with the Absolute Neutrophil Count in Patients with Hematological Malignancies Under Chemotherapy: An Application of Multilevel Models to a Preliminary Pharmacogenetic Study

PURPOSE: Neutropenia is a common event in patients undergoing cytotoxic chemotherapy for the treatment of a hematological malignancy. Some polymorphisms, as IL-6 −572C>G (rs1800796), IL-1β −31 G>A (rs1143627), and CARD8 304T>A (rs2043211), in genes related to the inflammatory process, could...

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Detalles Bibliográficos
Autores principales: Martinez, Matias F, Alveal, Enzo, Soto, Tomas G, Bustamante, Eva I, Ávila, Fernanda, Bangdiwala, Shrikant I, Flores, Ivonne, Benavides, Claudia, Morales, Ricardo, Varela, Nelson M, Quiñones, Luis A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450656/
https://www.ncbi.nlm.nih.gov/pubmed/32922063
http://dx.doi.org/10.2147/PGPM.S261208

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