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ScanITD: Detecting internal tandem duplication with robust variant allele frequency estimation
BACKGROUND: Internal tandem duplications (ITDs) are tandem duplications within coding exons and are important prognostic markers and drug targets for acute myeloid leukemia (AML). Next-generation sequencing has enabled the discovery of ITD at single-nucleotide resolution. ITD allele frequency is use...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450668/ https://www.ncbi.nlm.nih.gov/pubmed/32852038 http://dx.doi.org/10.1093/gigascience/giaa089 |