Omipalisib Inhibits Esophageal Squamous Cell Carcinoma Growth Through Inactivation of Phosphoinositide 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) and ERK Signaling

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a life-threatening digestive tract malignancy with no known curative treatment. This study aimed to investigate the antineoplastic effects of omipalisib and its underlying molecular mechanisms in ESCC using a high throughput screen. MATERIAL/M...

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Detalles Bibliográficos
Autores principales: Zhu, Dong-shan, Dong, Jing-yao, Xu, Yao-yao, Zhang, Xin-tong, Fu, Shi-bo, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450785/
https://www.ncbi.nlm.nih.gov/pubmed/32804918
http://dx.doi.org/10.12659/MSM.927106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450785/
https://www.ncbi.nlm.nih.gov/pubmed/32804918
http://dx.doi.org/10.12659/MSM.927106

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