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DLBCL with amplification of JAK2/PD-L2 exhibits PMBCL-like CNA pattern and worse clinical outcome resembling those with MYD88 L265P mutation

BACKGROUND: Recently, copy number alteration (CNA) of 9p24.1 were demonstrated in 10% of diffuse large b-cell lymphoma (DLBCL), with gene expression and mutation profiles that were similar to those of primary mediastinal large B-cell lymphoma (PMBCL). However, their CNA-based profile and clinical im...

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Detalles Bibliográficos
Autores principales: Xue, Xuemin, Huang, Wenting, Qiu, Tian, Guo, Lei, Ying, Jianming, Lv, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450805/
https://www.ncbi.nlm.nih.gov/pubmed/32854650
http://dx.doi.org/10.1186/s12885-020-07293-3