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DLBCL with amplification of JAK2/PD-L2 exhibits PMBCL-like CNA pattern and worse clinical outcome resembling those with MYD88 L265P mutation
BACKGROUND: Recently, copy number alteration (CNA) of 9p24.1 were demonstrated in 10% of diffuse large b-cell lymphoma (DLBCL), with gene expression and mutation profiles that were similar to those of primary mediastinal large B-cell lymphoma (PMBCL). However, their CNA-based profile and clinical im...
Autores principales: | Xue, Xuemin, Huang, Wenting, Qiu, Tian, Guo, Lei, Ying, Jianming, Lv, Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450805/ https://www.ncbi.nlm.nih.gov/pubmed/32854650 http://dx.doi.org/10.1186/s12885-020-07293-3 |
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