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A Rare Case of Creutzfeldt-Jakob Disease in an 80-Year-Old Male

Creutzfeldt-Jakob disease (CJD) is a rare, rapid and fatal human prion disease that causes neurodegeneration. Rapidly progressive dementia, quick involuntary muscle jerking and specific radiographic and laboratory findings are characteristic of the disease. CJD should not be ruled even if the clinic...

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Detalles Bibliográficos
Autores principales: Dervishi, Mario, Lambert, Travis, Markosyan Karapetyan, Maria, Warra, Nader, Iskenderian, Ziyad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450880/
https://www.ncbi.nlm.nih.gov/pubmed/32864281
http://dx.doi.org/10.7759/cureus.10038
Descripción
Sumario:Creutzfeldt-Jakob disease (CJD) is a rare, rapid and fatal human prion disease that causes neurodegeneration. Rapidly progressive dementia, quick involuntary muscle jerking and specific radiographic and laboratory findings are characteristic of the disease. CJD should not be ruled even if the clinical presentation is outside the common age range. Herein we present a case of an 80-year-old man with probable diagnosis of CJD. The absolute diagnosis of CJD can only be confirmed post-mortem with a brain biopsy.