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Miniaturized Piezo Force Sensor for a Medical Catheter and Implantable Device

[Image: see text] Real-time monitoring of intrabody pressures can benefit from the use of miniaturized force sensors during surgical interventions or for the recovery period thereafter. Herein, we present a force sensor made of poly(vinylidene fluoride)-co-trifluoroethylene (P(VDF-TrFE)) with a simp...

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Autores principales: Gil, Bruno, Li, Bing, Gao, Anzhu, Yang, Guang-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450887/
https://www.ncbi.nlm.nih.gov/pubmed/32879913
http://dx.doi.org/10.1021/acsaelm.0c00538
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author Gil, Bruno
Li, Bing
Gao, Anzhu
Yang, Guang-Zhong
author_facet Gil, Bruno
Li, Bing
Gao, Anzhu
Yang, Guang-Zhong
author_sort Gil, Bruno
collection PubMed
description [Image: see text] Real-time monitoring of intrabody pressures can benefit from the use of miniaturized force sensors during surgical interventions or for the recovery period thereafter. Herein, we present a force sensor made of poly(vinylidene fluoride)-co-trifluoroethylene (P(VDF-TrFE)) with a simple fabrication process that has been integrated into the tip of a medical catheter for intraluminal pressure monitoring, as well as into an implantable device with a power consumption of 180 μW obtained by the near-field communication (NFC) interface to monitor the arterial pulse at the subcutaneous level (≤1 cm). The pressure range supported by the sensor is below 40 kPa, with a signal responsivity of 0.63 μV/Pa and a mean lifetime expectancy of 400 000 loading cycles inside physiological conditions (12 kPa). The proposed sensor has been tested experimentally with synthetic anatomical models for the lungs (bronchoscopy) and subcutaneous tissue, as well as directly above the human carotid and radial arteries. Information about these pressure levels can provide insights about tissue homeostasis inside the body as fluid dynamics are altered in some health conditions affecting the hemodynamic and endocrine body systems, whereas for surgical interventions, precise control and estimation of the pressure exerted by a catheter over the internal walls are necessary to avoid endothelium injuries that lead to bleeding, liquid extravasation, or flow alteration associated with atheroma formation.
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spelling pubmed-74508872020-08-31 Miniaturized Piezo Force Sensor for a Medical Catheter and Implantable Device Gil, Bruno Li, Bing Gao, Anzhu Yang, Guang-Zhong ACS Appl Electron Mater [Image: see text] Real-time monitoring of intrabody pressures can benefit from the use of miniaturized force sensors during surgical interventions or for the recovery period thereafter. Herein, we present a force sensor made of poly(vinylidene fluoride)-co-trifluoroethylene (P(VDF-TrFE)) with a simple fabrication process that has been integrated into the tip of a medical catheter for intraluminal pressure monitoring, as well as into an implantable device with a power consumption of 180 μW obtained by the near-field communication (NFC) interface to monitor the arterial pulse at the subcutaneous level (≤1 cm). The pressure range supported by the sensor is below 40 kPa, with a signal responsivity of 0.63 μV/Pa and a mean lifetime expectancy of 400 000 loading cycles inside physiological conditions (12 kPa). The proposed sensor has been tested experimentally with synthetic anatomical models for the lungs (bronchoscopy) and subcutaneous tissue, as well as directly above the human carotid and radial arteries. Information about these pressure levels can provide insights about tissue homeostasis inside the body as fluid dynamics are altered in some health conditions affecting the hemodynamic and endocrine body systems, whereas for surgical interventions, precise control and estimation of the pressure exerted by a catheter over the internal walls are necessary to avoid endothelium injuries that lead to bleeding, liquid extravasation, or flow alteration associated with atheroma formation. American Chemical Society 2020-08-03 2020-08-25 /pmc/articles/PMC7450887/ /pubmed/32879913 http://dx.doi.org/10.1021/acsaelm.0c00538 Text en Copyright © 2020 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Gil, Bruno
Li, Bing
Gao, Anzhu
Yang, Guang-Zhong
Miniaturized Piezo Force Sensor for a Medical Catheter and Implantable Device
title Miniaturized Piezo Force Sensor for a Medical Catheter and Implantable Device
title_full Miniaturized Piezo Force Sensor for a Medical Catheter and Implantable Device
title_fullStr Miniaturized Piezo Force Sensor for a Medical Catheter and Implantable Device
title_full_unstemmed Miniaturized Piezo Force Sensor for a Medical Catheter and Implantable Device
title_short Miniaturized Piezo Force Sensor for a Medical Catheter and Implantable Device
title_sort miniaturized piezo force sensor for a medical catheter and implantable device
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450887/
https://www.ncbi.nlm.nih.gov/pubmed/32879913
http://dx.doi.org/10.1021/acsaelm.0c00538
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