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MMP-13 enzyme and pH responsive theranostic nanoplatform for osteoarthritis

Stimulus-responsive therapy permits precise control of therapeutic effect only at lesion of interest, which determines it a promising method for diagnosis and imaging-guided precision therapy. The acid environment and overexpressed matrix metalloproteinases-13 (MMP-13) are typical markers in osteoar...

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Detalles Bibliográficos
Autores principales: Lan, Qiumei, Lu, Rongbin, Chen, Haimin, Pang, Yunfen, Xiong, Feng, Shen, Chong, Qin, Zainen, Zheng, Li, Xu, Guojie, Zhao, Jinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450974/
https://www.ncbi.nlm.nih.gov/pubmed/32854712
http://dx.doi.org/10.1186/s12951-020-00666-7