Trisomy 21 and Coronavirus Disease 2019 in Pediatric Patients

We present 4 pediatric patients with trisomy 21 (T21) and associated comorbidities who developed coronavirus disease 2019 requiring hospitalization. A review of the literature revealed that comorbidities associated with T21 may predispose patients to severe disease. Children with T21 should be consi...

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Autores principales: Newman, Alexander M., Jhaveri, Ravi, Patel, Ami B., Tan, Tina Q., Toia, Jacqueline M., Arshad, Mehreen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451004/
https://www.ncbi.nlm.nih.gov/pubmed/32861693
http://dx.doi.org/10.1016/j.jpeds.2020.08.067
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author Newman, Alexander M.
Jhaveri, Ravi
Patel, Ami B.
Tan, Tina Q.
Toia, Jacqueline M.
Arshad, Mehreen
author_facet Newman, Alexander M.
Jhaveri, Ravi
Patel, Ami B.
Tan, Tina Q.
Toia, Jacqueline M.
Arshad, Mehreen
author_sort Newman, Alexander M.
collection PubMed
description We present 4 pediatric patients with trisomy 21 (T21) and associated comorbidities who developed coronavirus disease 2019 requiring hospitalization. A review of the literature revealed that comorbidities associated with T21 may predispose patients to severe disease. Children with T21 should be considered high risk and monitored carefully if infected with severe acute respiratory syndrome coronavirus 2.
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spelling pubmed-74510042020-08-28 Trisomy 21 and Coronavirus Disease 2019 in Pediatric Patients Newman, Alexander M. Jhaveri, Ravi Patel, Ami B. Tan, Tina Q. Toia, Jacqueline M. Arshad, Mehreen J Pediatr Brief Report We present 4 pediatric patients with trisomy 21 (T21) and associated comorbidities who developed coronavirus disease 2019 requiring hospitalization. A review of the literature revealed that comorbidities associated with T21 may predispose patients to severe disease. Children with T21 should be considered high risk and monitored carefully if infected with severe acute respiratory syndrome coronavirus 2. Elsevier Inc. 2021-01 2020-08-27 /pmc/articles/PMC7451004/ /pubmed/32861693 http://dx.doi.org/10.1016/j.jpeds.2020.08.067 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Brief Report
Newman, Alexander M.
Jhaveri, Ravi
Patel, Ami B.
Tan, Tina Q.
Toia, Jacqueline M.
Arshad, Mehreen
Trisomy 21 and Coronavirus Disease 2019 in Pediatric Patients
title Trisomy 21 and Coronavirus Disease 2019 in Pediatric Patients
title_full Trisomy 21 and Coronavirus Disease 2019 in Pediatric Patients
title_fullStr Trisomy 21 and Coronavirus Disease 2019 in Pediatric Patients
title_full_unstemmed Trisomy 21 and Coronavirus Disease 2019 in Pediatric Patients
title_short Trisomy 21 and Coronavirus Disease 2019 in Pediatric Patients
title_sort trisomy 21 and coronavirus disease 2019 in pediatric patients
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451004/
https://www.ncbi.nlm.nih.gov/pubmed/32861693
http://dx.doi.org/10.1016/j.jpeds.2020.08.067
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