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Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo
How antigen valency affects B cells in vivo during immune responses is not well understood. Here, using HIV immunogens with defined valencies ranging from 1 to 60, we investigated the role of antigen valency during different phases of B cell responses in vivo. Highly multimerized immunogens preferen...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451196/ https://www.ncbi.nlm.nih.gov/pubmed/32857950 http://dx.doi.org/10.1016/j.immuni.2020.08.001 |