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Surface plasmon resonance analysis of complex formation of therapeutic recombinant lysosomal enzymes with domain 9 of human cation-independent mannose 6-phosphate receptor

The efficacy of enzyme replacement therapy (ERT) for lysosomal storage diseases (LSDs) possibly depends on the cellular uptake of recombinant lysosomal enzymes (LEs), and it is known that cation-independent mannose 6-phosphate receptor (CI-M6PR) on the cell membrane is predominantly involved in the...

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Detalles Bibliográficos
Autores principales:	Kanzaki, Minori, Tsukimura, Takahiro, Chiba, Yasunori, Sakuraba, Hitoshi, Togawa, Tadayasu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451420/ https://www.ncbi.nlm.nih.gov/pubmed/32884906 http://dx.doi.org/10.1016/j.ymgmr.2020.100639

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