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The roles of replication-transcription conflict in mutagenesis and evolution of genome organization

Replication-transcription conflicts promote mutagenesis and give rise to evolutionary signatures, with fundamental importance to genome stability ranging from bacteria to metastatic cancer cells. This review focuses on the interplay between replication-transcription conflicts and the evolution of ge...

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Detalles Bibliográficos
Autores principales: Schroeder, Jeremy W., Sankar, T. Sabari, Wang, Jue D., Simmons, Lyle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451550/
https://www.ncbi.nlm.nih.gov/pubmed/32853297
http://dx.doi.org/10.1371/journal.pgen.1008987