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Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water

Marine species are increasingly important as a source of specific biological active metabolites. Marine species comprise almost half of global biodiversity. Oceans and sea are thus the biggest source of positive natural compounds that could be utilized in the pharmaceutical industry as functional co...

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Detalles Bibliográficos
Autores principales: Shanthi Kumari, K., Shivakrishna, Pabba, Ganduri, V.S. Ramakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451693/
https://www.ncbi.nlm.nih.gov/pubmed/32884422
http://dx.doi.org/10.1016/j.sjbs.2020.05.007
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author Shanthi Kumari, K.
Shivakrishna, Pabba
Ganduri, V.S. Ramakrishna
author_facet Shanthi Kumari, K.
Shivakrishna, Pabba
Ganduri, V.S. Ramakrishna
author_sort Shanthi Kumari, K.
collection PubMed
description Marine species are increasingly important as a source of specific biological active metabolites. Marine species comprise almost half of global biodiversity. Oceans and sea are thus the biggest source of positive natural compounds that could be utilized in the pharmaceutical industry as functional constituents. In the present study was to find out the wound healing property of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine source. The in vivo wound healing activity was studied using excision wound model. The KLUF 10 and KLUF13 ointment was prepared and used to determine wound healing activity in albino rats. Topical application of the ointment enhanced the contraction of wound in contrast with rat control group. KLUF13 had shown strong healing ability in wounds and had a positive influence on the various phases of wound repair.
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spelling pubmed-74516932020-09-02 Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water Shanthi Kumari, K. Shivakrishna, Pabba Ganduri, V.S. Ramakrishna Saudi J Biol Sci Article Marine species are increasingly important as a source of specific biological active metabolites. Marine species comprise almost half of global biodiversity. Oceans and sea are thus the biggest source of positive natural compounds that could be utilized in the pharmaceutical industry as functional constituents. In the present study was to find out the wound healing property of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine source. The in vivo wound healing activity was studied using excision wound model. The KLUF 10 and KLUF13 ointment was prepared and used to determine wound healing activity in albino rats. Topical application of the ointment enhanced the contraction of wound in contrast with rat control group. KLUF13 had shown strong healing ability in wounds and had a positive influence on the various phases of wound repair. Elsevier 2020-09 2020-05-11 /pmc/articles/PMC7451693/ /pubmed/32884422 http://dx.doi.org/10.1016/j.sjbs.2020.05.007 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Shanthi Kumari, K.
Shivakrishna, Pabba
Ganduri, V.S. Ramakrishna
Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water
title Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water
title_full Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water
title_fullStr Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water
title_full_unstemmed Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water
title_short Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water
title_sort wound healing activities of the bioactive compounds from micrococcus sp. ous9 isolated from marine water
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451693/
https://www.ncbi.nlm.nih.gov/pubmed/32884422
http://dx.doi.org/10.1016/j.sjbs.2020.05.007
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