The eIF4A inhibitor silvestrol sensitizes T-47D ductal breast carcinoma cells to external-beam radiotherapy

PURPOSE: eIF4A is an RNA helicase that forms part of the machinery of translation initiation. Proteomic analysis demonstrated eIF4A expression to be at least two-fold greater in a radioresistant derivative of T-47D breast cancer cells compared to parental cells. Inhibition of eIF4A has previously be...

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Detalles Bibliográficos
Autores principales: Webb, Thomas E., Davies, Marc, Maher, John, Sarker, Debashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451755/
https://www.ncbi.nlm.nih.gov/pubmed/32875125
http://dx.doi.org/10.1016/j.ctro.2020.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451755/
https://www.ncbi.nlm.nih.gov/pubmed/32875125
http://dx.doi.org/10.1016/j.ctro.2020.07.002

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