Cargando…

Negative selection of human T cells recognizing a naturally-expressed tissue-restricted antigen in the human thymus

During T cell development in mice, thymic negative selection deletes cells with the potential to recognize and react to self-antigens. In human T cell-dependent autoimmune diseases such as Type 1 diabetes, multiple sclerosis, and rheumatoid arthritis, T cells reactive to autoantigens are thought to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Madley, Rachel, Nauman, Grace, Danzl, Nichole, Borsotti, Chiara, Khosravi Maharlooei, Mohsen, Li, Hao Wei, Chavez, Estefania, Creusot, Remi J., Nakayama, Maki, Roep, Bart, Sykes, Megan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451786/ https://www.ncbi.nlm.nih.gov/pubmed/32875283 http://dx.doi.org/10.1016/j.jtauto.2020.100061

Ejemplares similares

Modeling human T1D-associated autoimmune processes
por: Khosravi-Maharlooei, Mohsen, et al.
Publicado: (2021)

High Throughput Human T Cell Receptor Sequencing: A New Window Into Repertoire Establishment and Alloreactivity
por: Fu, Jianing, et al.
Publicado: (2021)

Origin, phenotype and autoimmune potential of T cells in human immune system mice receiving neonatal human thymus tissue
por: Talaie, Tara, et al.
Publicado: (2023)

Soluble Antigen Arrays Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes
por: Firdessa-Fite, Rebuma, et al.
Publicado: (2021)

Posttransplant Hemophagocytic Lymphohistiocytosis Driven by Myeloid Cytokines and Vicious Cycles of T-Cell and Macrophage Activation in Humanized Mice
por: Yoshihara, Satoshi, et al.
Publicado: (2019)

Expression Pattern of Alternative Splicing Variants of Human Telomerase Reverse Transcriptase (hTERT) in Cancer Cell Lines Was not Associated with the Origin of the Cells
por: Khosravi- Maharlooei, Mohsen, et al.
Publicado: (2015)

Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression
por: Tree, Timothy I.M., et al.
Publicado: (2010)

Reticular network of the human thymus.
por: Yu, E., et al.
Publicado: (1993)

REGULATION OF AUTOSENSITIZATION : THE IMMUNE ACTIVATION AND SPECIFIC INHIBITION OF SELF-RECOGNIZING THYMUS-DERIVED LYMPHOCYTES
por: Cohen, Irun R., et al.
Publicado: (1973)

Spatially restricted JAG1-Notch signaling in human thymus provides suitable DC developmental niches
por: Martín-Gayo, Enrique, et al.
Publicado: (2017)

Reentry of T cells to the adult thymus is restricted to activated T cells
Publicado: (1991)

A COMPARISON BETWEEN DIFFERENT EXISTING METHODS USED TO SEPARATE EPIDERMAL CELLS FROM SKIN BIOPSIES FOR AUTOLOGOUS TRANSPLANTATION
por: Maharlooei, Mohsen Khosravi, et al.
Publicado: (2011)

Adipose Tissue Derived Multipotent Mesenchymal Stromal Cells Can Be Isolated Using Serum-free Media
por: Ahrari, Iman, et al.
Publicado: (2013)

Regulatory T-Cell Development in the Human Thymus
por: Caramalho, Íris, et al.
Publicado: (2015)

Histopathologic assessment of cultured human thymus
por: Hale, Laura P., et al.
Publicado: (2020)

Screening of the growth of thymus of human fetuses
por: Asghar, Adil, et al.
Publicado: (2019)

Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors
por: Szomolay, Barbara, et al.
Publicado: (2016)

The human fetal thymus generates invariant effector γδ T cells
por: Tieppo, Paola, et al.
Publicado: (2019)

Human islet T cells are highly reactive to preproinsulin in type 1 diabetes
por: Anderson, Amanda M., et al.
Publicado: (2021)

Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin
por: Danzl, Nichole M., et al.
Publicado: (2010)

Fetal thymus in growth-restricted fetuses due to placental insufficiency
por: Takeno, Marisa Akemi, et al.
Publicado: (2023)

Humanized Mice Reveal New Insights Into the Thymic Selection of Human Autoreactive CD8(+) T Cells
por: Li, Yang, et al.
Publicado: (2019)

Expression Pattern of Immunoproteasome Subunits in Human Thymus
por: Oh, Kwon Ik, et al.
Publicado: (2009)

Polymorphism of Hassall's corpuscles in thymus of human fetuses
por: Asghar, Adil, et al.
Publicado: (2012)

Human APECED; a Sick Thymus Syndrome?
por: Arstila, T. Petteri, et al.
Publicado: (2013)

Minipuberty and Sexual Dimorphism in the Infant Human Thymus
por: Moreira-Filho, Carlos Alberto, et al.
Publicado: (2018)

Thyroid-Related Protein Expression in the Human Thymus
por: Kim, Mi Jeong, et al.
Publicado: (2017)

Transcriptomes of antigen presenting cells in human thymus
por: Gabrielsen, Ingvild S. M., et al.
Publicado: (2019)

Human TCR-gamma+/delta+, CD8+ T lymphocytes recognize tetanus toxoid in an MHC-restricted fashion
Publicado: (1989)

Highly restricted expression of the thymus leukemia antigens on intestinal epithelial cells
Publicado: (1991)

Novel HLA-B7-restricted human metapneumovirus epitopes enhance viral clearance in mice and are recognized by human CD8(+) T cells
por: Miranda-Katz, Margot, et al.
Publicado: (2021)

Identification of Novel Thymic Epithelial Cell Subsets Whose Differentiation Is Regulated by RANKL and Traf6
por: Danzl, Nichole M., et al.
Publicado: (2014)

Differential Expression Of Adhesion Molecules Within The Human Thymus
por: Reza, Julie Naima, et al.
Publicado: (1994)

Dynamics of thymus organogenesis and colonization in early human development
por: Farley, Alison M., et al.
Publicado: (2013)

Expression and Distribution of the Adrenomedullin System in Newborn Human Thymus
por: De Martin, Sara, et al.
Publicado: (2014)

Human tumor antigens recognized by T lymphocytes
Publicado: (1996)

Bacterial cell division is recognized by the septin cytoskeleton for restriction by autophagy
por: Krokowski, Sina, et al.
Publicado: (2019)

Essential Microenvironment for Thymopoiesis is Preserved in Human Adult and Aged Thymus
por: Shiraishi, J., et al.
Publicado: (2003)

The thymus leukemia antigen binds human and mouse CD8
Publicado: (1991)

Location of T cell and major histocompatibility complex antigens in the human thymus
Publicado: (1980)

Cannot write session to /tmp/vufind_sessions/sess_fp7gl9il5t9808qg8ume7t2jkv