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Increases of iASPP-Keap1 interaction mediated by syringin enhance synaptic plasticity and rescue cognitive impairments via stabilizing Nrf2 in Alzheimer's models

Oxidative stress is an important pathogenic manifestation of Alzheimer's disease (AD) that contributes to synaptic dysfunction, which precedes Aβ accumulation and neurofibrillary tangle formation. However, the molecular machineries that govern the decline of antioxidative defence in AD remains...

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Detalles Bibliográficos
Autores principales:	Wang, Chun-Yan, Zhang, Qi, Xun, Zhe, Yuan, Lin, Li, Ruonan, Li, Xiang, Tian, Shu-Yu, Xin, Na, Xu, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452088/ https://www.ncbi.nlm.nih.gov/pubmed/32828017 http://dx.doi.org/10.1016/j.redox.2020.101672

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