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Exosomal Transfer of LCP1 Promotes Osteosarcoma Cell Tumorigenesis and Metastasis by Activating the JAK2/STAT3 Signaling Pathway

Increasing evidence indicates that lymphocyte cytosolic protein 1 (LCP1) overexpression contributes to tumor progression; however, its role in osteosarcoma (OS) remains unclear. We aimed to investigate the potential effect of LCP1 in OS and the underlying mechanisms. We first demonstrated that LCP1...

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Detalles Bibliográficos
Autores principales: Ge, Xuhui, Liu, Wei, Zhao, Wene, Feng, Shuang, Duan, Ao, Ji, Chengyue, Shen, Kai, Liu, Wanshun, Zhou, Jiawen, Jiang, Dongdong, Rong, Yuluo, Gong, Fangyi, Wang, Jiaxing, Xu, Zhiyang, Li, Xiaoyan, Fan, Jin, Wei, Yongzhong, Bai, Jianling, Cai, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452114/
https://www.ncbi.nlm.nih.gov/pubmed/32810692
http://dx.doi.org/10.1016/j.omtn.2020.07.025