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Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy

Immuno-oncology approaches that utilize T cell receptors (TCRs) are becoming highly attractive because of their potential to target virtually all cellular proteins, including cancer-specific epitopes, via the recognition of peptide-human leukocyte antigen (pHLA) complexes presented at the cell surfa...

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Detalles Bibliográficos
Autores principales:	Crean, Rory M., MacLachlan, Bruce J., Madura, Florian, Whalley, Thomas, Rizkallah, Pierre J., Holland, Christopher J., McMurran, Catriona, Harper, Stephen, Godkin, Andrew, Sewell, Andrew K., Pudney, Christopher R., van der Kamp, Marc W., Cole, David K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452143/ https://www.ncbi.nlm.nih.gov/pubmed/32913893 http://dx.doi.org/10.1016/j.omto.2020.07.008

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