Cargando…

Glucocorticoid Priming of Nonviral Gene Delivery to hMSCs Increases Transfection by Reducing Induced Stresses

Human mesenchymal stem cells (hMSCs) are under study for cell and gene therapeutics because of their immunomodulatory and regenerative properties. Safe and efficient gene delivery could increase hMSC clinical potential by enabling expression of transgenes for control over factor production, behavior...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hamann, Andrew, Kozisek, Tyler, Broad, Kelly, Pannier, Angela K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452153/ https://www.ncbi.nlm.nih.gov/pubmed/32913879 http://dx.doi.org/10.1016/j.omtm.2020.07.014

Ejemplares similares

Comparison of promoter, DNA vector, and cationic carrier for efficient transfection of hMSCs from multiple donors and tissue sources
por: Kozisek, Tyler, et al.
Publicado: (2021)

Mechanisms of unprimed and dexamethasone‐primed nonviral gene delivery to human mesenchymal stem cells
por: Hamann, Andrew, et al.
Publicado: (2018)

High-throughput screening of clinically approved drugs that prime nonviral gene delivery to human Mesenchymal stem cells
por: Kozisek, Tyler, et al.
Publicado: (2020)

Magnetic Nanoparticle Based Nonviral MicroRNA Delivery into Freshly Isolated CD105(+) hMSCs
por: Schade, Anna, et al.
Publicado: (2014)

IRX5 promotes adipogenesis of hMSCs by repressing glycolysis
por: Jiang, Bulin, et al.
Publicado: (2022)

Proliferation and Osteogenic Differentiation of hMSCs on Biomineralized Collagen
por: de Melo Pereira, Daniel, et al.
Publicado: (2020)

Nucleic acid delivery to mesenchymal stem cells: a review of nonviral methods and applications
por: Hamann, Andrew, et al.
Publicado: (2019)

(18)F- based Quantification of the Osteogenic Potential of hMSCs
por: Grossner, Tobias, et al.
Publicado: (2020)

hMSCs possess the potential to differentiate into DP cells in vivo and in vitro
por: Wu, Minjuan, et al.
Publicado: (2012)

hMSCs as an alternative therapeutic option for asthma with neutrophil mediated inflammation
por: Cruz, Fernanda F., et al.
Publicado: (2018)

hMSCs suppress neutrophil-dominant airway inflammation in a murine model of asthma
por: Hong, Gyong Hwa, et al.
Publicado: (2017)

Low dose effect of bisphosphonates on hMSCs osteogenic response to titanium surface in vitro
por: Alqhtani, N.R., et al.
Publicado: (2017)

Decoupling the role of chemistry and microstructure in hMSCs response to an osteoinductive calcium phosphate ceramic
por: Galván-Chacón, V.P., et al.
Publicado: (2022)

hMSCs in contact with DMSO for cryopreservation: Experiments and modeling of osmotic injury and cytotoxic effect
por: Traversari, Gabriele, et al.
Publicado: (2022)

The role of surface chemistry-induced cell characteristics on nonviral gene delivery to mouse fibroblasts
por: Kasputis, Tadas, et al.
Publicado: (2012)

Xeno-Hybrid Bone Graft Releasing Biomimetic Proteins Promotes Osteogenic Differentiation of hMSCs
por: Zhu, Hao, et al.
Publicado: (2020)

TLR3-/4-Priming Differentially Promotes Ca(2+) Signaling and Cytokine Expression and Ca(2+)-Dependently Augments Cytokine Release in hMSCs
por: Park, Kyoung Sun, et al.
Publicado: (2016)

Manipulation of miRNA activity accelerates osteogenic differentiation of hMSCs in engineered 3D scaffolds
por: Mariner, Peter D, et al.
Publicado: (2012)

Platelet lysate outperforms FCS and human serum for co-culture of primary human macrophages and hMSCs
por: Tylek, Tina, et al.
Publicado: (2019)

Transplantation of hMSCs Genome Edited with LEF1 Improves Cardio-Protective Effects in Myocardial Infarction
por: Cho, Hyun-Min, et al.
Publicado: (2020)

Impact of Tranexamic Acid on Chondrocytes and Osteogenically Differentiated Human Mesenchymal Stromal Cells (hMSCs) In Vitro
por: Wagenbrenner, Mike, et al.
Publicado: (2020)

Comparative study on the effects of substrate stiffness on cell morphology and focal adhesion expression between hMSCs and AFSCs
por: Lowry, B, et al.
Publicado: (2012)

P2 Receptors Influence hMSCs Differentiation towards Endothelial Cell and Smooth Muscle Cell Lineages
por: Zhang, Yu, et al.
Publicado: (2020)

Precision 3D printed meniscus scaffolds to facilitate hMSCs proliferation and chondrogenic differentiation for tissue regeneration
por: Deng, Xingyu, et al.
Publicado: (2021)

TMT-Based Quantitative Proteomics Analysis Reveals Differentially Expressed Proteins between Different Sources of hMSCs
por: Naudot, Marie, et al.
Publicado: (2023)

TSG-6 Produced by hMSCs Delays the Onset of Autoimmune Diabetes by Suppressing Th1 Development and Enhancing Tolerogenicity
por: Kota, Daniel J., et al.
Publicado: (2013)

Long Term Expansion of Bone Marrow-Derived hMSCs on Novel Synthetic Microcarriers in Xeno-Free, Defined Conditions
por: Hervy, Martial, et al.
Publicado: (2014)

Differentiation of Definitive Endoderm from Human Induced Pluripotent Stem Cells on hMSCs Feeder in a Defined Medium
por: Jaafarpour, Zahra, et al.
Publicado: (2016)

Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF‐1r Onto the Primary Cilium Associated With Cilia Elongation
por: Dalbay, Melis T., et al.
Publicado: (2015)

Evaluation of osteogenic differentiation of human mesenchymal stem cells (hMSCs) on random and aligned polycaprolactone-polyaniline-gelatin scaffolds
por: KarbalaeiMahdi, Ali, et al.
Publicado: (2023)

The response of human macrophages to 3D printed titanium antibacterial implants does not affect the osteogenic differentiation of hMSCs
por: Garmendia Urdalleta, Amaia, et al.
Publicado: (2023)

MiR-33a Controls hMSCS Osteoblast Commitment Modulating the Yap/Taz Expression Through EGFR Signaling Regulation
por: Costa, Viviana, et al.
Publicado: (2019)

The increase of NADH fluorescence lifetime is associated with the metabolic change during osteogenic differentiation of human mesenchymal stem cells (hMSCs)
por: Guo, Han Wen, et al.
Publicado: (2012)

Efficient Differentiation of Human Induced Pluripotent Stem Cell (hiPSC) Derived Hepatocyte-Like Cells on hMSCs Feeder
por: Mobarra, Naser, et al.
Publicado: (2014)

Verification of Long-Term Genetic Stability of hMSCs during Subculture after Internalization of Sunflower-Type Nanoparticles (SF-NPs)
por: Park, Ji Sun, et al.
Publicado: (2018)

Volumetric imaging of human mesenchymal stem cells (hMSCs) for non-destructive quantification of 3D cell culture growth
por: Benavides, Oscar R., et al.
Publicado: (2023)

Nonviral gene delivery system
por: Yang, Ningning
Publicado: (2012)

The osteogenic response of undifferentiated human mesenchymal stem cells (hMSCs) to mechanical strain is inversely related to body mass index of the donor
por: Friedl, Gerald, et al.
Publicado: (2009)

Electro-magnetic field promotes osteogenic differentiation of BM-hMSCs through a selective action on Ca(2+)-related mechanisms
por: Petecchia, Loredana, et al.
Publicado: (2015)

Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-α Stimulated Gene/Protein 6
por: He, Zhigang, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_lpt62u6ud7cilqfnq4b8ehejoj