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DOK7 Gene Therapy Enhances Neuromuscular Junction Innervation and Motor Function in Aged Mice

Muscle denervation at the neuromuscular junction (NMJ), the essential synapse between motor neuron and skeletal muscle, is associated with age-related motor impairment. Therefore, improving muscle innervation at aged NMJs may be an effective therapeutic strategy for treating the impairment. We previ...

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Detalles Bibliográficos
Autores principales:	Ueta, Ryo, Sugita, Satoshi, Minegishi, Yoshihiko, Shimotoyodome, Akira, Ota, Noriyasu, Ogiso, Noboru, Eguchi, Takahiro, Yamanashi, Yuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452162/ https://www.ncbi.nlm.nih.gov/pubmed/32758427 http://dx.doi.org/10.1016/j.isci.2020.101385

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